GPC2-CAR T cells tuned for low antigen density mediate potent
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Descrição
Pediatric cancers often mimic fetal tissues and express proteins normally silenced postnatally that could serve as immune targets. We developed T cell…
Antigen density quantification of cell-surface immunotherapy targets by flow cytometry: Multi-antigen assay of neuroblastoma bone marrow metastasis - ScienceDirect
GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity - ScienceDirect
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CAR T cells targeting tumor-associated exons of glypican 2 regress neuroblastoma in mice. - Abstract - Europe PMC
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